The following is a list of 2009 journal publications from the Division of Gastroenterology faculty and fellows. This list is organized by month of publication and then alphabetically by title. Links to abstracts and further reading are inlcuded when available. To learn more about the research interests of our faculty and fellows, please visit the Directory section of our website.

Bilirubin chemistry and metabolism; harmful and protective aspects. Vítek L, Ostrow JD. Curr Pharm Des. 2009;15(25):2869-83. Read Abstract »

Novel diagnostic and prognostic modalities in inflammatory bowel disease. Zisman TL, Rubin DT. Gastroenterol Clin North Am. 2009 Dec;38(4):729-52. Read Abstract »

Pattern of diagnostic evaluation for the causes of pediatric acute liver failure: an opportunity for quality improvement. Narkewicz MR, Dell Olio D, Karpen SJ, Murray KF, Schwarz K, Yazigi N, Zhang S, Belle SH, Squires RH; Pediatric Acute Liver Failure Study Group. J Pediatr. 2009 Dec;155(6):801-806.e1 [Epub 2009 Jul 29]. Read Abstract »

Clonal expansions in ulcerative colitis identify patients with neoplasia. Salk JJ, Salipante SJ, Risques RA, Crispin DA, Li L, Bronner MP, Brentnall TA, Rabinovitch PS, Horwitz MS, Loeb LA. Read Abstract »

Fulminant hepatic failure after use of the herbal weight-loss supplement exilis. McDonnell WM, Bhattacharya R, Halldorson JB. Ann Intern Med. 2009 Nov 3;151(9):673-4. Read Abstract »

Management of antithrombotic agents for endoscopic procedures. Prepared by: ASGE STANDARDS OF PRACTICE COMMITTEE, Anderson MA, Ben-Menachem T, Gan SI, Appalaneni V, Banerjee S, Cash BD, Fisher L, Harrison ME, Fanelli RD, Fukami N, Ikenberry SO, Jain R, Khan K, Lee Krinsky M, Lichtenstein DR, Shen B, Strohmeyer L, Baron T, Dominitz JA. Gastrointest Endosc. 2009 Nov 2 [Epub ahead of print]. Read Abstract »

Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Shah AG, Lydecker A, Murray K, Tetri BN, Contos MJ, Sanyal AJ; Nash Clinical Research Network. Clin Gastroenterol Hepatol. 2009 Oct;7(10):1104-12 [Epub 2009 Jun 10]. Read Abstract »

Does flexible sigmoidoscopy reduce colorectal cancer incidence and mortality? Dominitz JA, Robertson DJ. Gastroenterology. 2009 Oct;137(4):1529-31 [Epub 2009 Aug 28]. Read Abstract »

Evolving concepts in Clostridium difficile colitis. Diggs NG, Surawicz CM. Curr Gastroenterol Rep. 2009 Oct;11(5):400-5. Read Abstract »

Imaging of subsquamous Barrett's epithelium with ultrahigh-resolution optical coherence tomography: a histologic correlation study. Cobb MJ, Hwang JH, Upton MP, Chen Y, Oelschlager BK, Wood DE, Kimmey MB, Li X. Gastrointest Endosc. 2009 Oct 19 [Epub ahead of print]. Read Abstract »

Pathologic diagnosis of biliary atresia on liver biopsy: is tissue the issue? Yeh MM. J Gastroenterol Hepatol. 2009 Jun;24(6):936-8. Read Abstract »

Recommendations for Screening, Monitoring, and Referral of Pediatric Chronic Hepatitis B. Haber BA, Block JM, Jonas MM, Karpen SJ, London WT, McMahon BJ, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB. Pediatrics. 2009 Oct 5 [Epub ahead of print]. Read Abstract »

Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice. Larter CZ, Yeh MM, Van Rooyen DM, Teoh NC, Brooling J, Hou JY, Williams J, Clyne M, Nolan CJ, Farrell GC. J Gastroenterol Hepatol. 2009 Oct;24(10):1658-68. Read Abstract »

Selection criteria for genetic assessment of patients with familial melanoma. Leachman SA, Carucci J, Kohlmann W, Banks KC, Asgari MM, Bergman W, Bianchi-Scarrà G, Brentnall T, et al. J Am Acad Dermatol. 2009 Oct;61(4):677.e1-14. Read Abstract »

Serious Complications Within 30 Days of Screening and Surveillance Colonoscopy are Uncommon. Ko CW, Riffle S, Michaels L, Morris C, Holub J, Shapiro JA, Ciol MA, Kimmey MB, Seeff LC, Lieberman D. Clin Gastroenterol Hepatol. 2009 Oct 20 [Epub ahead of print]. Read Abstract »

Survival after orthotopic liver transplantation: the impact of antibody against hepatitis B core antigen in the donor. Yu L, Koepsell T, Manhart L, Ioannou G. Liver Transpl. 2009 Oct;15(10):1343-50. Read Abstract »

To perform a biopsy or not to perform a biopsy? Does confocal endomicroscopy provide the answer for surveillance in Barrett's esophagus? Hwang JH. Gastrointest Endosc. 2009 Oct;70(4):655-7. Read Abstract »

Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model. Borinstein SC, Conerly M, Dzieciatkowski S, Biswas S, Washington MK, Trobridge P, Henikoff S, Grady WM. Mol Carcinog. 2009 Sep 23 [Epub ahead of print]. Read Abstract »

Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation Maloney E, Sweet IR, Hockenbery DM, Pham M, Rizzo NO, Tateya S, Handa P, Schwartz MW, Kim F. Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1370-5 [Epub 2009 Jun 18]. Read Abstract »

Cytomegalovirus in inflammatory bowel disease: time for another look? Julka K, Surawicz CM. Gastroenterology. 2009 Sep;137(3):1163-6 [Epub 2009 Jul 25]. Read Abstract »

Effectiveness of a provider reminder on fecal occult blood test follow-up. Larson MF, Ko CW, Dominitz JA. Dig Dis Sci. 2009 Sep;54(9):1991-6. Epub 2009 Mar 3. Read Abstract »

Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3. Laiko M, Murtazina R, Malyukova I, Zhu C, Boedeker EC, Gutsal O, O'Malley R, Cole RN, Tarr PI, Murray KF, Kane A, Donowitz M, Kovbasnjuk O. Exp Cell Res. 2009 Sep 8 [Epub ahead of print]. Read Abstract »

Silymarin Inhibits in Vitro T Cell Proliferation and Cytokine Production in Hepatitis C Virus Infection. Morishima C, Shuhart MC, Wang CC, Paschal DM, Apodaca MC, Liu Y, Sloan DD, Graf TN, Oberlies NH, Lee DY, Jerome KR, Polyak SJ. Gastroenterology. 2009 Sep 23 [Epub ahead of print]. Read Abstract »

Treatment of nonalcoholic fatty liver disease in children: TONIC trial design. Lavine JE, Schwimmer JB, Molleston JP, Scheimann AO, Murray KF, Abrams SH, Rosenthal P, Sanyal AJ, Robuck PR, Brunt EM, Unalp A, Tonascia J; The NASH CRN Research Group. Contemp Clin Trials. 2009 Sep 15 [Epub ahead of print]. Read Abstract »

Assessment of familiality, obesity, and other risk factors for early age of cancer diagnosis in adenocarcinomas of the esophagus and gastroesophageal junction. Chak A, Falk G, Grady WM, Kinnard M, Elston R, Mittal S, King JF, Willis JE, Kondru A, Brock W, Barnholtz-Sloan J. Am J Gastroenterol. 2009 Aug;104(8):1913-21 [Epub 2009 Jun 2]. Read Abstract »

Association between the peroxisome proliferator-activated receptor gamma Pro12Ala variant and haplotype and pancreatic cancer in a high-risk cohort of smokers: a pilot study. Fesinmeyer MD, Stanford JL, Brentnall TA, Mandelson MT, Farin FM, Srinouanprachanh S, Afsharinejad Z, Goodman GE, Barnett MJ, Austin MA. Read Abstract »

Autoimmune hepatitis. Mieli-Vergani G, Heller S, Jara P, Vergani D, Chang MH, Fujisawa T, González-Peralta RP, Kelly D, Mohan N, Shah U, Murray KF. J Pediatr Gastroenterol Nutr. 2009 Aug;49(2):158-64. Read Abstract »

Bilirubin inhibits the TNFalpha-related induction of three endothelial adhesion molecules. Mazzone GL, Rigato I, Ostrow JD, Bossi F, Bortoluzzi A, Sukowati CH, Tedesco F, Tiribelli C. Biochem Biophys Res Commun. 2009 Aug 21;386(2):338-44 [Epub 2009 Jun 10]. Read Abstract »

Comparative analysis of PCR-based biomarker assay methods for colorectal polyp detection from fecal DNA. Ausch C, Kim YH, Tsuchiya KD, Dzieciatkowski S, Washington MK, Paraskeva C, Radich J, Grady WM. Clin Chem. 2009 Aug;55(8):1559-63 [Epub 2009 Jun 18]. Read Abstract »

Liver transplantation at the extremes of the body mass index. Dick AA, Spitzer AL, Seifert CF, Deckert A, Carithers RL Jr, Reyes JD, Perkins JD. Liver Transpl. 2009 Aug;15(8):968-77. Read Abstract »

Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the United States population. Ioannou GN, Morrow OB, Connole ML, Lee SP. Hepatology. 2009 Jul;50(1):175-84. Read Abstract »

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry. Morrish F, Isern N, Sadilek M, Jeffrey M, Hockenbery DM. Oncogene. 2009 Jul 9;28(27):2485-91 [Epub 2009 May 18]. Read Abstract »

Differences in hepatic phenotype between hemochromatosis patients with HFE C282Y homozygosity and other HFE genotypes. Cheng R, Barton JC, Morrison ED, Phatak PD, Krawitt EL, Gordon SC, Kowdley KV. J Clin Gastroenterol. 2009 Jul;43(6):569-73. Read Abstract »

Effects of lipopolysaccharide on platelet-derived growth factor isoform and receptor expression in cultured rat common bile duct fibroblasts and cholangiocytes Kim TH, Moon JH, Savard CE, Kuver R, Lee SP. J Gastroenterol Hepatol. 2009 Jul;24(7):1218-25. Read Abstract »

High-resolution OCT balloon imaging catheter with astigmatism correction. Xi J, Huo L, Wu Y, Cobb MJ, Hwang JH, Li X. Opt Lett. 2009 Jul 1;34(13):1943-5. Read Abstract »

TGF-beta receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-beta. Rojas A, Padidam M, Cress D, Grady WM. Biochim Biophys Acta. 2009 Jul;1793(7):1165-73 [Epub 2009 Feb 12]. Read Abstract »

Unbound (free) bilirubin: improving the paradigm for evaluating neonatal jaundice. Ahlfors CE, Wennberg RP, Ostrow JD, Tiribelli C. Clin Chem. 2009 Jul;55(7):1288-99 [Epub 2009 May 7]. Read Abstract »

Collagenous gastritis, a new spectrum of disease in pediatric patients: two case reports. Suskind D, Wahbeh G, Murray K, Christie D, Kapur RP. Cases J. 2009 Jun 10;2:7511. Read Abstract »

Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study Carnevale-Schianca F, Leisenring W, Martin PJ, Furlong T, Schoch G, Anasetti C, Appelbaum FR, Carpenter PA, Deeg HJ, Kiem HP, Storb R, McDonald GB, Nash RA. Biol Blood Marrow Transplant. 2009 Jun;15(6):749-56. Read Abstract »

Nonadenomatous dysplasia in barrett esophagus: a clinical, pathologic, and DNA content flow cytometric study. Rucker-Schmidt RL, Sanchez CA, Blount PL, Ayub K, Li X, Rabinovitch PS, Reid BJ, Odze RD. Am J Surg Pathol. 2009 Jun;33(6):886-93. Read Abstract »

Preclinical in vivo evaluation of an extracorporeal HIFU device for ablation of pancreatic tumors. Hwang JH, Wang YN, Warren C, Upton MP, Starr F, Zhou Y, Mitchell SB. Ultrasound Med Biol. 2009 Jun;35(6):967-75 [Epub 2009 Feb 8]. Read Abstract »

Refractory Colitis Following Anti-CTLA4 Antibody Therapy: Analysis of Mucosal FOXP3(+) T Cells. Lord JD, Hackman RC, Moklebust A, Thompson JA, Higano CS, Chielens D, Steinbach G, McDonald GB. Dig Dis Sci. 2009 Jun 9 [Epub ahead of print]. Read Abstract »

Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology? Markowitz J, Kugathasan S, Dubinsky M, Mei L, Crandall W, LeLeiko N, Oliva-Hemker M, Rosh J, Evans J, Mack D, Otley A, Pfefferkorn M, Bahar R, Vasiliauskas E, Wahbeh G, et al. Inflamm Bowel Dis. 2009 May;15(5):714-9. Read Abstract »

Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma. Paulson TG, Maley CC, Li X, Li H, Sanchez CA, Chao DL, Odze RD, Vaughan TL, Blount PL, Reid BJ. Clin Cancer Res. 2009 May 15;15(10):3305-14 [Epub 2009 May 5]. Read Abstract »

Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma. Ahmad I, Iyer A, Marginean CE, Yeh MM, Ferrell L, Qin L, Bifulco CB, Jain D. Hum Pathol. 2009 May;40(5):726-34 [Epub 2009 Jan 20]. Read Abstract »

Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration Diabetologia. 2009 May;52(5):921-31 [Epub 2009 Feb 14]. Read Abstract »

Physical activity decreases diverticular complications. Strate LL, Liu YL, Aldoori WH, Giovannucci EL. Am J Gastroenterol. 2009 May;104(5):1221-30 [Epub 2009 Apr 14]. Read Abstract »

TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway. Trobridge P, Knoblaugh S, Washington MK, Munoz NM, Tsuchiya KD, Rojas A, Song X, Ulrich CM, Sasazuki T, Shirasawa S, Grady WM. Gastroenterology. 2009 May;136(5):1680-8.e7 [Epub 2009 Feb 4]. Read Abstract »

Translation of an STR-based biomarker into a clinically compatible SNP-based platform for loss of heterozygosity. Kissel HD, Galipeau PC, Li X, Reid BJ. Cancer Biomark. 2009;5(3):143-58. Read Abstract »

Colorectal cancer screening with computed tomographic colonography. Dominitz JA, Robertson DJ. Gastroenterology. 2009 Apr;136(4):1451-3 [Epub 2009 Feb 21]. Read Abstract »

Bilirubin induced neurological damage: from the cell to the newborn. Ostrow JD, Tiribelli C. Curr Pharm Des. 2009;15(25):2868. Read Abstract »

Endoscopy by nonphysicians. American Society for Gastrointestinal Endoscopy, Ikenberry SO, Anderson MA, Banerjee S, Baron TH, Dominitz JA, Gan SI, Harrison ME, Jagannath S, Levy M, Lichtenstein D, Shen B, Fanelli RD, Stewart L, Khan K. Gastrointest Endosc. 2009 Apr;69(4):767-70. Read Abstract »

Enhanced chemotherapeutic drug delivery to tumor tissue by high intensity focused ultrasound. Korean J Gastroenterol. 2009 Apr;53(4):216-20. Jung JT, Lee DH, Hwang JH. Read Abstract »

Management of chronic hepatitis B in children. Shah U, Kelly D, Chang MH, Fujisawa T, Heller S, González-Peralta RP, Jara P, Mieli-Vergani G, Mohan N, Murray KF. J Pediatr Gastroenterol Nutr. 2009 Apr;48(4):399-404. Read Abstract »

Marked iron in liver explants in the absence of major hereditary hemochromatosis gene defects: a risk factor for cardiac failure Fenton H, Torbenson M, Vivekanandan P, Yeh MM, Hart J, Ferrell L. Transplantation. 2009 Apr 27;87(8):1256-60. Read Abstract »

New endoscopic and cytologic tools for cancer surveillance in the digestive tract. Seibel EJ, Brentnall TA, Dominitz JA. Gastrointest Endosc Clin N Am. 2009 Apr;19(2):299-307. Read Abstract »

Proteomics on Fixed Tissue Specimens - A Review. Reimel BA, Pan S, May DH, Shaffer SA, Goodlett DR, McIntosh MW, Yerian LM, Bronner MP, Chen R, Brentnall TA. Curr Proteomics. 2009 Apr 1;6(1):63-69. Read Abstract »

Quantitative proteomics investigation of pancreatic intraepithelial neoplasia. Pan S, Chen R, Reimel BA, Crispin DA, Mirzaei H, Cooke K, Coleman JF, Lane Z, Bronner MP, Goodlett DR, McIntosh MW, Traverso W, Aebersold R, Brentnall TA. Electrophoresis. 2009 Apr;30(7):1132-44. Read Abstract »

Retraction. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Van Parijs L, Refaeli Y, Lord JD, Nelson BH, Abbas AK, Baltimore D. Immunity. 2009 Apr 17;30(4):611. Read Abstract »

Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression. Farrell GC, Larter CZ, Hou JY, Zhang RH, Yeh MM, Williams J, dela Pena A, Francisco R, Osvath SR, Brooling J, Teoh N, Sedger LM. Read Abstract »

Bak to basics of colonocyte renewal. Susnow NJ, Hockenbery DM. Gastroenterology. 2009 Mar;136(3):763-6 [Epub 2009 Jan 22]. Read Abstract »

Impact of hepatitis C virus infection on children and their caregivers: quality of life, cognitive, and emotional outcomes. Rodrigue JR, Balistreri W, Haber B, Jonas MM, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Smith LJ, Schwarz KB, Robuck P, Barton B, González-Peralta RP. J Pediatr Gastroenterol Nutr. 2009 Mar;48(3):341-7. Read Abstract »

Initial therapy of acute graft-versus-host disease with low-dose prednisone does not compromise patient outcomes. Mielcarek M, Storer BE, Boeckh M, Carpenter PA, McDonald GB, Deeg HJ, Nash RA, Flowers ME, Doney K, Lee S, Marr KA, Furlong T, Storb R, Appelbaum FR, Martin PJ. Blood. 2009 Mar 26;113(13):2888-94 [Epub 2009 Nov 10]. Read Abstract »

Gallbladder epithelial cells that engraft in mouse liver can differentiate into hepatocyte-like cells. Lee SP, Savard CE, Kuver R. Am J Pathol. 2009 Mar;174(3):842-53 [Epub 2009 Feb 13]. Read Abstract »

Reining in recurrent Clostridium difficile infection--who's at risk? Surawicz CM. Gastroenterology. 2009 Apr;136(4):1152-4 [Epub 2009 Feb 25]. Read Abstract »

Bcl-2 family proteins as regulators of oxidative stress. Susnow N, Zeng L, Margineantu D, Hockenbery DM. Semin Cancer Biol. 2009 Feb;19(1):42-9 [Epub 2009 Dec 24]. Semin Cancer Biol. 2009 Feb;19(1):42-9 [Epub 2009 Dec 24]. Read Abstract »

Effective treatment of unconjugated hyperbilirubinemia with oral bile salts in Gunn rats. Cuperus FJ, Hafkamp AM, Havinga R, Vitek L, Zelenka J, Tiribelli C, Ostrow JD, Verkade HJ. Gastroenterology. 2009 Feb;136(2):673-82.e1 [Epub 2009 Nov 6]. Read Abstract »

Hepatitis C virus and allogeneic stem cell transplantation still matters! Socié G, de Latour RP, McDonald GB. Haematologica. 2009 Feb;94(2):170-2. Read Abstract »

Mass spectrometry based targeted protein quantification: methods and applications. Pan S, Aebersold R, Chen R, Rush J, Goodlett DR, McIntosh MW, Zhang J, Brentnall TA. J Proteome Res. 2009 Feb;8(2):787-97. Read Abstract »

Renal thrombotic microangiopathy after hematopoietic cell transplant: role of GVHD in pathogenesis. Changsirikulchai S, Myerson D, Guthrie KA, McDonald GB, Alpers CE, Hingorani SR. Clin J Am Soc Nephrol. 2009 Feb;4(2):345-53 [Epub 2009 Jan 14]. Read Abstract »

Should liver transplantation in patients with model for end-stage liver disease scores < or = 14 be avoided? A decision analysis approach Perkins JD, Halldorson JB, Bakthavatsalam R, Fix OK, Carithers RL Jr, Reyes JD. Read Abstract »

The gut microbiota: a microbial arsenal protecting us from infectious and radiation-induced diarrhea. Damman CJ, Surawicz CM. Gastroenterology. 2009 Feb;136(2):722-4 [Epub 2009 Dec 25]. Read Abstract »

Emerging infections of the gastrointestinal tract. Schlenker C, Surawicz CM. Best Pract Res Clin Gastroenterol. 2009;23(1):89-99. Read Abstract »

Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis. Malyukova I, Murray KF, Zhu C, Boedeker E, Kane A, Patterson K, Peterson JR, Donowitz M, Kovbasnjuk O. Am J Physiol Gastrointest Liver Physiol. 2009 Jan;296(1):G78-92 [Epub 2009 Oct 30]. Read Abstract »

Obesity increases the risks of diverticulitis and diverticular bleeding. Strate LL, Liu YL, Aldoori WH, Syngal S, Giovannucci EL. Gastroenterology. 2009 Jan;136(1):115-122.e1 [Epub 2009 Sep 25]. Read Abstract »

Pancreatic acinar tissue in liver explants: a morphologic and immunohistochemical study. Kuo FY, Swanson PE, Yeh MM. Am J Surg Pathol. 2009 Jan;33(1):66-71. Read Abstract »

Prevention of nonsteroidal anti-inflammatory drug-induced gastropathy. Schlansky B, Hwang JH. J Gastroenterol. 2009;44 Suppl 19:44-52 [Epub 2009 Jan 16]. Read Abstract »

The cytotoxic effect of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells is modulated by the expression level of MRP1 but not MDR1. Corich L, Aranda A, Carrassa L, Bellarosa C, Ostrow JD, Tiribelli C. Biochem J. 2009 Jan 1;417(1):305-12. Read Abstract »