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Iris W. Liou, MD
Clinical Associate Professor
Biography

Dr. Liou is a member of the Acute Liver Failure Study Group, a multicenter clinical study investigating clinical outcomes of acute liver failure. Her interests include hepatocellular carcinoma, including adjuvant therapy after liver transplantation; management of a tissue repository for the study of liver disease and evaluation of fibrosis due to recurrent hepatitis C in the post-transplant setting; clinical outcomes following liver transplantation; and the natural history of hepatitis B.

Recent Publications
Displaying 20 Most Recent Publications from PubMed

October 2018. Healthcare Resource Utilization and Costs by Disease Severity in an Insured National Sample of US Patients with Chronic Hepatitis B. Nguyen MH, Ozbay AB, Liou I, Meyer N, Gordon SC, Dusheiko G, Lim JK. J Hepatol. 2018 Oct 1. pii: S0168-8278(18)32440-1. doi: 10.1016/j.jhep.2018.09.021. [Epub ahead of print]

May 2018. Toward consensus reporting of radiation-induced liver toxicity in the treatment of primary liver malignancies: Defining clinically relevant endpoints. Chapman TR, Bowen SR, Schaub SK, Yeung RH, Kwan SW, Park JO, Yu L, Harris WP, Johnson GE, Liou IW, Nyflot MJ, Apisarnthanarax S. Pract Radiat Oncol. 2018 May - Jun;8(3):157-166. doi: 10.1016/j.prro.2017.10.013. Epub 2017 Nov 4.

August 2017. Acute Liver Failure Due to Echovirus 9 Associated With Persistent B-Cell Depletion From Rituximab. Bajema KL, Simonson PD, Greninger AL, Çoruh B, Pottinger PS, Bhattacharya R, Liou IW, Jalikis FG, Fligner CL, Rakita RM. Open Forum Infect Dis. 2017 Aug 14;4(3):ofx174. doi: 10.1093/ofid/ofx174. eCollection 2017 Summer.

April 2017. An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients With Acute Liver Injury or Failure. Roberts DW, Lee WM, Hinson JA, Bai S, Swearingen CJ, Stravitz RT, Reuben A, Letzig L, Simpson PM, Rule J, Fontana RJ, Ganger D, Reddy KR, Liou I, Fix O, James LP. Clin Gastroenterol Hepatol. 2017 Apr;15(4):555-562.e3. doi: 10.1016/j.cgh.2016.09.007. Epub 2016 Sep 15.

June 2016. Measuring total liver function on sulfur colloid SPECT/CT for improved risk stratification and outcome prediction of hepatocellular carcinoma patients. Bowen SR, Chapman TR, Borgman J, Miyaoka RS, Kinahan PE, Liou IW, Sandison GA, Vesselle HJ, Nyflot MJ, Apisarnthanarax S. EJNMMI Res. 2016 Dec;6(1):57. doi: 10.1186/s13550-016-0212-9. Epub 2016 Jun 27.

June 2016. Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Reuben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Smith A, Brown R, Crippin J, Harrison ME, Koch D, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hassanein T, Hanje AJ, Olson J, Subramanian R, Karvellas C, Hameed B, Sherker AH, Robuck P, Lee WM. Ann Intern Med. 2016 Jun 7;164(11):724-32. doi: 10.7326/M15-2211. Epub 2016 Apr 5.

May 2016. Development and Pilot of a Checklist for Management of Acute Liver Failure in the Intensive Care Unit. Fix OK, Liou I, Karvellas CJ, Ganger DR, Forde KA, Subramanian RM, Boylan A, Hanje J, Stravitz RT, Lee WM; Acute Liver Failure Study Group. PLoS One. 2016 May 13;11(5):e0155500. doi: 10.1371/journal.pone.0155500. eCollection 2016.

February 2016. Aging of liver transplant registrants and recipients: trends and impact on waitlist outcomes, post-transplantation outcomes and transplant-related survival benefit. Su F, Yu L, Berry K, Liou IW, Landis CS, Rayhill SC, Reyes JD, Ioannou GN. Gastroenterology. 2016 Feb;150(2):441-453.e6. doi: 10.1053/j.gastro.2015.10.043. Epub 2015 Oct 30.

January 2016. Association Between Transjugular Intrahepatic Porto-systemic Shunt and Survival in Patients with Cirrhosis. Berry K, Lerrigo R, Liou IW, Ioannou GN. Clin Gastroenterol Hepatol. 2016 Jan;14(1):118-23. doi: 10.1016/j.cgh.2015.06.042. Epub 2015 Jul 17.

September 2015. Comprehensive Care of Patients with Chronic Liver Disease. James J, Liou IW. Med Clin North Am. 2015 Sep;99(5):913-33. doi: 10.1016/j.mcna.2015.05.001. Epub 2015 Jul 2. Review.

March 2015. Portal Vein Thrombosis Is Not Associated With Increased Mortality Among Patients With Cirrhosis. Berry K, Taylor J, Liou IW, Ioannou GN. Clin Gastroenterol Hepatol. 2015 Mar;13(3):585-93. doi: 10.1016/j.cgh.2014.10.010. Epub 2014 Oct 18.

February 2015. 2-year outcomes in Initial survivors with Acute Liver failure: Results from a Prospective, Multicenter Study. Fontana RJ, Ellerbe C, Durkalski VE, Rangnekar A, Reddy KR, Stravitz T, McGuire B, Davern T, Reuben A, Liou I, Fix O, Ganger DR, Chung RT, Schilsky M, Han S, Hynan LS, Sanders C, Lee WM; The US Acute Liver Failure Study Group. Liver Int. 2015 Feb;35(2):370-80. doi: 10.1111/liv.12632. Epub 2014 Jul 28.

January 2015. Transjugular Intrahepatic Portosystemic Shunt Placement During Pregnancy: A Case Series of Five Patients. Ingraham CR, Padia SA, Johnson GE, Easterling TR, Liou IW, Kanal KM, Valji K. Ingraham CR, Padia SA, Johnson GE, Easterling TR, Liou IW, Kanal KM, Valji K.

December 2014. Congestive hepatic fibrosis score: a novel histologic assessment of clinical severity. Dai DF, Swanson PE, Krieger EV, Liou IW, Carithers RL, Yeh MM. Mod Pathol. 2014 Dec;27(12):1552-8. doi: 10.1038/modpathol.2014.79. Epub 2014 Jun 13.

September 2014. D-MELD risk capping improves post-transplant and overall mortality under markov microsimulation. Halldorson JB, Jr RL, Bhattacharya R, Bakthavatsalam R, Liou IW, Dick AA, Reyes JD, Perkins JD. World J Transplant. 2014 Sep 24;4(3):206-15. doi: 10.5500/wjt.v4.i3.206.

January 2014. Management of End-stage Liver Disease. Liou IW. Med Clin North Am. 2014 Jan;98(1):119-52. doi: 10.1016/j.mcna.2013.09.006. Epub 2013 Oct 30.

June 2013. Phase I adjuvant trial of sorafenib in patients with hepatocellular carcinoma after orthotopic liver transplantation. Jia N, Liou I, Halldorson J, Carithers R, Perkins J, Reyes J, Yeh M, Stohr E, Rao S, Lin EH. Anticancer Res. 2013 Jun;33(6):2797-800.

July 2012. Proteome and computational analyses reveal new insights into the mechanisms of hepatitis C virus mediated liver disease post-transplantation. Diamond DL, Krasnoselsky AL, Burnum KE, Monroe ME, Webb-Robertson BJ, McDermott JE, Yeh MM, Dzib JF, Susnow N, Strom S, Proll SC, Belisle SE, Purdy DE, Rasmussen AL, Walters KA, Jacobs JM, Gritsenko MA, Camp DG, Bhattacharya R, Perkins JD, Carithers RL Jr, Liou IW, Larson AM, Benecke A, Waters KM, Smith RD, Katze MG. Hepatology. 2012 Jul;56(1):28-38. doi: 10.1002/hep.25649. Epub 2012 Apr 24.

December 2010. The use of hepatitis B core antibody-positive donor livers does not appear to have a deleterious effect on graft survival in liver transplantation for hepatitis C. Rayhill S, Schwartz J, Ham J, Carithers R, Lei Y, Bhattacharya R, Liou I, Landis C, Lamaye A, Rakita R, Dick A, Healey P, Halldorson J, Bhakthavatsalam R, Perkins J, Reyes J. Transplant Proc. 2010 Dec;42(10):4141-4. doi: 10.1016/j.transproceed.2010.09.023.

May 2008. Role of liver transplantation in acute liver failure. Liou IW, Larson AM Semin Liver Dis. 2008 May;28(2):201-9

November 2006. Bilirubin and colorectal cancer: authors' reply. Ioannou GN, Liou IW, Weiss NS Aliment Pharmacol Ther. 2006 Nov;24(10):1504

June 2006. Serum bilirubin and colorectal cancer risk: a population-based cohort study. Ioannou GN, Liou IW, Weiss NS Aliment Pharmacol Ther. 2006 Jun 1;23(11):1637-42

March 2006. Natural History of Nonalcoholic Steatohepatitis. Liou I, Kowdley KV. J Clin Gastroenterol 2006 Mar;40 Suppl 1:S11-S16

Contact Info
Education

Fellowship in Transplant Hepatology, University of Washington School of Medicine, Seattle, WA

Fellowship in Gastroenterology, University of Washington School of Medicine, Seattle, WA

Residency in Medicine, University of Washington School of Medicine, Seattle, WA

M.D., University of Washington School of Medicine, Seattle, WA

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