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Anne M. Larson, MD
Clinical Professor & Chief, Liver Clinic,
UW Medicine-Northwest Hospital
Biography

Dr. Larson is the Clinic Chief of the UW Medicine/Northwest Hospital Liver Clinic and a UW Clinical Professor of Medicine. She is a nationally recognized clinician, researcher and lecturer, the author of numerous peer-reviewed publications, and is recognized as a leader in the field of hepatology.

Dr. Larson will be seeing all types of liver patients and has a strong interest in promoting customized treatment plans. This includes liver disease management, medical and surgical options and working closely with the UW liver transplant team.

Dr. Larson earned her bachelor’s degree, M.D and internal medicine residency training from the University of Washington. She completed her gastroenterology fellowship at the University of California San Diego, and returned to the University of Washington for her Hepatology fellowship

After nearly 11 years on the faculty at the University of Washington, she travelled to the University of Texas Southwestern in Dallas, Texas, where she was the medical director of the Liver Transplantation Program and Clinical Hepatology. She returned to Seattle in 2011 and was the director of the Liver Center at Swedish Medical Center. She received her medical degree and completed her internal medicine residency at the University of Washington School of Medicine in Seattle.

She is Board Certified: Internal Medicine, Gastroenterology, Transplant Hepatology. She is a fellow of the American Association for the Study of Liver Disease, American Gastroenterological Association, and the American College of Physicians. She is a member of the American Society of Transplantation.

Recent Publications
Displaying 20 Most Recent Publications from PubMed

June 2018. Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality. Ganger DR, Rule J, Rakela J, Bass N, Reuben A, Stravitz RT, Sussman N, Larson AM, James L, Chiu C, Lee WM; Acute Liver Failure Study Group. Am J Gastroenterol. 2018 Jun 27. doi: 10.1038/s41395-018-0160-2. [Epub ahead of print]

June 2016. Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Reuben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Smith A, Brown R, Crippin J, Harrison ME, Koch D, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hassanein T, Hanje AJ, Olson J, Subramanian R, Karvellas C, Hameed B, Sherker AH, Robuck P, Lee WM. Ann Intern Med. 2016 Jun 7;164(11):724-32. doi: 10.7326/M15-2211. Epub 2016 Apr 5.

May 2015. Palliative care for patients with end-stage liver disease. Larson AM. Curr Gastroenterol Rep. 2015 May;17(5):440. doi: 10.1007/s11894-015-0440-6. Review.

February 2015. Risk factors and outcomes of acute kidney injury in patients with acute liver failure. Tujios SR, Hynan LS, Vazquez MA, Larson AM, Seremba E, Sanders CM, Lee WM; Acute Liver Failure Study Group. Clin Gastroenterol Hepatol. 2015 Feb;13(2):352-9. doi: 10.1016/j.cgh.2014.07.011. Epub 2014 Jul 11.

January 2014. Liver disease and its treatment. Preface. Larson AM. Med Clin North Am. 2014 Jan;98(1):xv-xvi. doi: 10.1016/j.mcna.2013.10.013.

October 2013. Diarrhea in solid-organ transplant recipients: a review of the evidence. Pant C, Deshpande A, Larson A, O'Connor J, Rolston DD, Sferra TJ. Curr Med Res Opin. 2013 Oct;29(10):1315-28. doi: 10.1185/03007995.2013.816278. Epub 2013 Aug 1.

July 2012. Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients Rasmussen AL, Tchitchek N, Susnow NJ, Krasnoselsky AL, Diamond DL, Yeh MM, Proll SC, Korth MJ, Walters KA, Lederer S, Larson AM, Carithers RL, Benecke A, Katze MG. Hepatology. 2012 Jul;56(1):17-27. doi: 10.1002/hep.25612. Epub 2012 Jun 5

July 2012. Proteome and computational analyses reveal new insights into the mechanisms of hepatitis C virus mediated liver disease post-transplantation. Diamond DL, Krasnoselsky AL, Burnum KE, Monroe ME, Webb-Robertson BJ, McDermott JE, Yeh MM, Dzib JF, Susnow N, Strom S, Proll SC, Belisle SE, Purdy DE, Rasmussen AL, Walters KA, Jacobs JM, Gritsenko MA, Camp DG, Bhattacharya R, Perkins JD, Carithers RL Jr, Liou IW, Larson AM, Benecke A, Waters KM, Smith RD, Katze MG. Hepatology. 2012 Jul;56(1):28-38. doi: 10.1002/hep.25649. Epub 2012 Apr 24.

June 2012. Adult liver transplantation in the United States. Bachir NM, Larson AM. Am J Med Sci. 2012 Jun;343(6):462-9. doi: 10.1097/MAJ.0b013e3182308b66. Review.

March 2012. Introduction to the revised American Association for the Study of Liver Diseases Position Paper on acute liver failure 2011. Lee WM, Stravitz RT, Larson AM. Hepatology. 2012 Mar;55(3):965-7. doi: 10.1002/hep.25551.

May 2011. Adult liver transplantation in the USA. Alqahtani SA, Larson AM. Curr Opin Gastroenterol. 2011 May;27(3):240-7. doi: 10.1097/MOG.0b013e3283457d5d. Review.

February 2011. Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure. Khandelwal N, James LP, Sanders C, Larson AM, Lee WM; Acute Liver Failure Study Group. Hepatology. 2011 Feb;53(2):567-76. doi: 10.1002/hep.24060. Epub 2011 Jan 10.

June 2010. Acetaminophen dose does not predict outcome in acetaminophen-induced acute liver failure. Gregory B, Larson AM, Reisch J, Lee WM; Acute Liver Failure Study Group. J Investig Med. 2010 Jun;58(5):707-10. doi: 10.231/JIM.0b013e3181db8764.

May 2010. Diagnosis and management of acute liver failure. Larson AM. Curr Opin Gastroenterol. 2010 May;26(3):214-21. doi: 10.1097/MOG.0b013e32833847c5. Review.

September 2009. Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure. Lee WM, Hynan LS, Rossaro L, Fontana RJ, Stravitz RT, Larson AM, Davern TJ 2nd, Murray NG, McCashland T, Reisch JS, Robuck PR; Acute Liver Failure Study Group. Gastroenterology. 2009 Sep;137(3):856-64, 864.e1. doi: 10.1053/j.gastro.2009.06.006. Epub 2009 Jun 12.

June 2009. Thinking through acetaminophen hepatotoxicity and liver transplantation: choosing worthy recipients. Lee WM, Larson AM, Arenas J. Liver Transpl. 2009 Jun;15(6):567-9. doi: 10.1002/lt.21728.

July 2008. Acute liver failure. Larson AM. Dis Mon. 2008 Jul;54(7):457-85. doi: 10.1016/j.disamonth.2008.03.008.

July 2008. Identifying risk for recurrent hepatocellular carcinoma after liver transplantation: implications for surveillance studies and new adjuvant therapies. Chan EY, Larson AM, Fix OK, Yeh MM, Levy AE, Bakthavatsalam R, Halldorson JB, Reyes JD, Perkins JD. Liver Transpl. 2008 Jul;14(7):956-65. doi: 10.1002/lt.21449.

May 2008. Role of liver transplantation in acute liver failure. Liou IW, Larson AM Semin Liver Dis. 2008 May;28(2):201-9

May 2008. Ischemic cholangiopathy following liver transplantation from donation after cardiac death donors. Chan EY, Olson LC, Kisthard JA, Perkins JD, Bakthavatsalam R, Halldorson JB, Reyes JD, Larson AM, Levy AE. Liver Transpl. 2008 May;14(5):604-10. doi: 10.1002/lt.21361.

September 2007. Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction. Diamond DL, Jacobs JM, Paeper B, Proll SC, Gritsenko MA, Carithers RL Jr, Larson AM, Yeh MM, Camp DG 2nd, Smith RD, Katze MG Hepatology. 2007 Sep;46(3):649-57

August 2007. Acetaminophen hepatotoxicity. Larson AM. Clin Liver Dis. 2007 Aug;11(3):525-48, vi. Review.

June 2007. Elevated troponin I levels in acute liver failure: is myocardial injury an integral part of acute liver failure? Parekh NK, Hynan LS, De Lemos J, Lee WM; Acute Liver Failure Study Group. Hepatology. 2007 Jun;45(6):1489-95.

May 2007. The expression of transforming growth factor-alpha in cirrhosis, dysplastic nodules, and hepatocellular carcinoma: an immunohistochemical study of 70 cases. Yeh MM, Larson AM, Campbell JS, Fausto N, Rulyak SJ, Swanson PE. Am J Surg Pathol. 2007 May;31(5):681-9.

April 2007. Incidence of minor complications and time lost from normal activities after screening or surveillance colonoscopy. Ko CW, Riffle S, Shapiro JA, Saunders MD, Lee SD, Tung BY, Kuver R, Larson AM, Kowdley KV, <br>Kimmey MB Gastrointest Endosc. 2007 Apr;65(4):648-656. Epub 2006 Dec 14

April 2007. Recipient and donor factors influence the incidence of graft-vs.-host disease in liver transplant patients Chan EY, Larson AM, Gernsheimer TB, <br>Kowdley KV, Carithers RL, Reyes JD, Perkins JD Liver Transpl. 2007 Apr;13(4):516-22

December 2006. Fulminant hepatitis A virus infection in the United States: Incidence, prognosis, and outcomes. Taylor RM, Davern T, Munoz S, Han SH, McGuire B, Larson AM, Hynan L, Lee WM, Fontana RJ; US Acute Liver Failure Study Group. Hepatology. 2006 Dec;44(6):1589-97.

June 2006. Endotheliitis in chronic viral hepatitis: a comparison with acute cellular rejection and non-alcoholic steatohepatitis. Yeh MM, Larson AM, Tung BY, Swanson PE, Upton MP. Am J Surg Pathol. 2006 Jun;30(6):727-33.

May 2006. Integrating palliative care for liver transplant candidates: "too well for transplant, too sick for life". Larson AM, Curtis JR. JAMA. 2006 May 10;295(18):2168-76.

March 2006. Measurement of serum acetaminophen-protein adducts in patients with acute liver failure. Davern TJ 2nd, James LP, Hinson JA, Polson J, Larson AM, Fontana RJ, Lalani E, Munoz S, Shakil AO, Lee WM; Acute Liver Failure Study Group. Gastroenterology. 2006 Mar;130(3):687-94.

Contact Info
Education

​Senior Fellowship, Transplant Hepatology, University of Washington, Seattle, WA

Clinical Fellowship, Gastroenterology, University of California, San Diego

Residency, Internal Medicine, University of Washington, Seattle, WA

MD, with Honors, University of Washington, School of Medicine, Seattle, WA

BS, Microbiology, University of Washington, Seattle, WA

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